Short Pretreatment with Calcitriol Is Far Superior to Continuous Treatment in Stimulating Proliferation and Osteogenic Differentiation of Human Adipose Stem Cells

Short Pretreatment with Calcitriol Is Far Superior to Continuous Treatment in Stimulating Proliferation and Osteogenic Differentiation of Human Adipose Stem Cells

Objective: This study investigated whether short stimulation (30 minutes) of human adipose stem cells (hASCs) with 1,25-dihydroxyvitamin D3 (calcitriol or 1,25-(OH)2VitD3), fitting within the surgical procedure time frame, suffices to induce osteogenic differentiation, and compared this with conti...

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Bibliographic Details
Main Authors: Fatemeh Mokhtari-Jafari, Ghassem Amoabediny, Mohammad Mehdi Dehghan, Marco N. Helder, Behrouz Zandieh-Doulabi, Jenneke Klein-Nulend
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2020-10-01
Series:Cell Journal
Subjects:
1
25-dihydroxy vitamin d3
adipose-derived stem cells
bone
osteogenesis
proliferation
Online Access:https://celljournal.org/journal/article/abstract/6773

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