Integron activity accelerates the evolution of antibiotic resistance

Integron activity accelerates the evolution of antibiotic resistance

Mobile integrons are widespread genetic platforms that allow bacteria to modulate the expression of antibiotic resistance cassettes by shuffling their position from a common promoter. Antibiotic stress induces the expression of an integrase that excises and integrates cassettes, and this unique reco...

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Bibliographic Details
Main Authors: Célia Souque, José Antonio Escudero, R Craig MacLean
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
P. aeruginosa
experimental evolution
antibiotic resistance
integron
Online Access:https://elifesciences.org/articles/62474

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