Visualisation of DCP, a nerve agent mimic, in Catfish brain by a simple chemosensor

Abstract A chemosensor, 3-aminophenol-based rhodamine conjugate (ARC) has been developed for visualisation of diethylchlorophosphate (DCP), mimic of a chemical warfare agent, in Catfish brain. The simple detection of DCP by “turn-on” fluorescence property of the chemosensor makes it unique for easy...

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Bibliographic Details
Main Authors: Himadri Sekhar Sarkar, Ayndrila Ghosh, Sujoy Das, Pulak Kumar Maiti, Sudipta Maitra, Sukhendu Mandal, Prithidipa Sahoo
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21780-5
Description
Summary:Abstract A chemosensor, 3-aminophenol-based rhodamine conjugate (ARC) has been developed for visualisation of diethylchlorophosphate (DCP), mimic of a chemical warfare agent, in Catfish brain. The simple detection of DCP by “turn-on” fluorescence property of the chemosensor makes it unique for easy and rapid in vivo and in vitro detection of DCP with the detection limit of 5.6 nM.
ISSN:2045-2322