Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions

Summary: Neurogenesis in the developing neocortex relies on extensive mitosis of radial glial cells (RGCs) in the apical surface. The nuclear migration of epithelial-like RGCs is fundamentally important for proper mitosis, but how the apical processes of RGCs are anchored to ensure the nucleokinetic...

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Bibliographic Details
Main Authors: Jingjing Wang, Tong Li, Jing-Li Wang, Zhiheng Xu, Wenxiang Meng, Qing-Feng Wu
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720314844