Darier-White disease in siblings responding to isotretinoin

Darier-White disease in siblings responding to isotretinoin

Darier-White disease (keratosis follicularis) is a rare disorder of keratinization involving the epidermis, mucous membranes, and nails. It is said to occur as a result of mutation in the ATP2A2 gene located on chromosome 12q23-24.1. In this article we present the case of two brothers with exacerbat...

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Bibliographic Details
Main Authors: Ramesh M Bhat, Krithi Raviraj Ullal, Anita Caroline Pinto, D Sukumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2010-01-01
Series:Indian Dermatology Online Journal
Subjects:
Darier-White disease
keratosis follicularis
isotretinoin
Online Access:http://www.idoj.in/article.asp?issn=2229-5178;year=2010;volume=1;issue=1;spage=18;epage=20;aulast=Bhat
Description
Summary:Darier-White disease (keratosis follicularis) is a rare disorder of keratinization involving the epidermis, mucous membranes, and nails. It is said to occur as a result of mutation in the ATP2A2 gene located on chromosome 12q23-24.1. In this article we present the case of two brothers with exacerbations of Darier-White disease who responded very well to systemic retinoids without any side effects within 2 weeks of commencing treatment.
ISSN:2229-5178

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