The Therapeutic Potential of Orphan GPCRs, GPR35 and GPR55

The G protein-coupled receptor (GPCR) superfamily of integral proteins is the largest family of signal transducers, comprised of ~1000 members. Considering their prevalence and functional importance, it’s not surprising that ~60% of drugs target GPCRs. Regardless, there exists a subset of the GPCR s...

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Bibliographic Details
Main Authors: Patricia Hodapp Reggio, Derek M Shore
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Pharmacology
Subjects:
LPI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00069/full