Structural characterization of the Saccharomyces cerevisiae THO complex by small-angle X-ray scattering.

Structural characterization of the Saccharomyces cerevisiae THO complex by small-angle X-ray scattering.

The THO complex participates during eukaryotic mRNA biogenesis in coupling transcription to formation and nuclear export of translation-competent messenger ribonucleoprotein particles. In Saccharomyces cerevisiae, THO has been defined as a heteropentamer composed of the Tho2p, Hpr1p, Tex1p, Mft1p, a...

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Bibliographic Details
Main Authors:	Jesper Buchhave Poulsen, Lee Edward Sanderson, Emil Dandanell Agerschou, Emil Dedic, Thomas Boesen, Ditlev E Brodersen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4111604?pdf=render

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