Proteínas quinases: características estruturais e inibidores químicos Kinase protein: structural features and chemical inhibitors

Proteínas quinases: características estruturais e inibidores químicos Kinase protein: structural features and chemical inhibitors

<abstract language="eng">Protein kinases are one of the largest protein families and they are responsible for regulation of a great number of signal transduction pathways in cells, through the phosphorylation of serine, threonine, or tyrosine residues. Deregulation of these enzymes i...

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Bibliographic Details
Main Authors: Bárbara V. Silva, Bruno A. C. Horta, Ricardo Bicca de Alencastro, Angelo C. Pinto
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2009-01-01
Series:Química Nova
Subjects:
kinase
chemical inhibitors
cell signaling
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000200032

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