Transcriptional hallmarks of cancer cell lines reveal an emerging role of branched chain amino acid catabolism
Abstract A comparative analysis between cancer cell lines and healthy dividing cells was performed using data (289 microarrays and 50 RNA-seq samples) from 100 different cancer cell lines and 6 types of healthy stem cells. The analysis revealed two large-scale transcriptional events that characteriz...
Main Authors: | Ieva Antanavičiūtė, Valeryia Mikalayeva, Ieva Ceslevičienė, Gintarė Milašiūtė, Vytenis Arvydas Skeberdis, Sergio Bordel |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-08329-8 |
Similar Items
-
Genome scale metabolic models as tools for drug design and personalized medicine.
by: Vytautas Raškevičius, et al.
Published: (2018-01-01) -
Fatty Acid Synthesis and Degradation Interplay to Regulate the Oxidative Stress in Cancer Cells
by: Valeryia Mikalayeva, et al.
Published: (2019-03-01) -
Midbody: From the Regulator of Cytokinesis to Postmitotic Signaling Organelle
by: Ieva Antanavičiūtė, et al.
Published: (2018-07-01) -
Hyperthermia Differently Affects Connexin43 Expression and Gap Junction Permeability in Skeletal Myoblasts and HeLa Cells
by: Ieva Antanavičiūtė, et al.
Published: (2014-01-01) -
The effect of nutmeg essential oil constituents on Novikoff hepatoma cell viability and communication through Cx43 gap junctions
by: Rokas Mickus, et al.
Published: (2021-03-01)