SOX10-regulated promoter use defines isoform-specific gene expression in Schwann cells

Abstract Background Multicellular organisms adopt various strategies to tailor gene expression to cellular contexts including the employment of multiple promoters (and the associated transcription start sites (TSSs)) at a single locus that encodes distinct gene isoforms. Schwann cells—the myelinatin...

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Bibliographic Details
Main Authors: Elizabeth A. Fogarty, Jacob O. Kitzman, Anthony Antonellis
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-020-06963-7