Genetic and epigenetic control of gene expression by CRISPR–Cas systems [version 1; referees: 3 approved]

The discovery and adaption of bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems has revolutionized the way researchers edit genomes. Engineering of catalytically inactivated Cas variants (nuclease-deficient or nuclease-deactivated [dCas]) co...

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Bibliographic Details
Main Authors: Albert Lo, Lei Qi
Format: Article
Language:English
Published: F1000 Research Ltd 2017-05-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-747/v1