Genetic and epigenetic control of gene expression by CRISPR–Cas systems [version 1; referees: 3 approved]
The discovery and adaption of bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems has revolutionized the way researchers edit genomes. Engineering of catalytically inactivated Cas variants (nuclease-deficient or nuclease-deactivated [dCas]) co...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2017-05-01
|
Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/6-747/v1 |