Long term adaptation of a microbial population to a permanent metabolic constraint: overcoming thymineless death by experimental evolution of <it>Escherichia coli</it>
<p>Abstract</p> <p>Background</p> <p>To maintain populations of microbial cells under controlled conditions of growth and environment for an indefinite duration is a prerequisite for experimentally evolving natural isolates of wild-type species or recombinant strains. T...
Main Authors: | Mutzel Rupert, Bellalou Jacques, de Crécy-Lagard Valérie A, Marlière Philippe |
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Format: | Article |
Language: | English |
Published: |
BMC
2001-11-01
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Series: | BMC Biotechnology |
Online Access: | http://www.biomedcentral.com/1472-6750/1/10 |
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