LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3
Abstract Background Acute spinal cord injury (SCI) could cause mainly two types of pathological sequelae, the primary mechanical injury, and the secondary injury. The macrophage in SCI are skewed toward the M1 phenotype that might cause the failure to post-SCI repair. Methods SCI model was establish...
Main Authors: | Jiahui Zhou, Zhiyue Li, Tianding Wu, Qun Zhao, Qiancheng Zhao, Yong Cao |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-020-01805-5 |
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