The human retinoblastoma gene is imprinted.
Genomic imprinting is an epigenetic process leading to parent-of-origin-specific DNA methylation and gene expression. To date, approximately 60 imprinted human genes are known. Based on genome-wide methylation analysis of a patient with multiple imprinting defects, we have identified a differentiall...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-12-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2791201?pdf=render |