PITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy
Abstract Developments in the field of proton beam therapy (PBT) have recently crossed the tipping point wherein the modality is now more versatile than ever before, with possibilities and likely indications expanding rapidly. However the pace of evidence generation lags behind the developments in th...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-06-01
|
Series: | Radiation Oncology |
Online Access: | http://link.springer.com/article/10.1186/s13014-020-01538-y |
id |
doaj-b8bc785442814ab88c44ff0bba9f2488 |
---|---|
record_format |
Article |
spelling |
doaj-b8bc785442814ab88c44ff0bba9f24882020-11-25T03:29:46ZengBMCRadiation Oncology1748-717X2020-06-011511310.1186/s13014-020-01538-yPITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapySrinivas Chilukuri0Pankaj Kumar Panda1Rakesh Jalali2Apollo Proton Cancer CentreApollo Proton Cancer CentreApollo Proton Cancer CentreAbstract Developments in the field of proton beam therapy (PBT) have recently crossed the tipping point wherein the modality is now more versatile than ever before, with possibilities and likely indications expanding rapidly. However the pace of evidence generation lags behind the developments in the field. Generating quality evidence has its own set of challenges owing to complexities of conducting randomized controlled trials, which are the hallmark of level 1 evidence generation. Here we discuss various challenges to clinical evidence generation in PBT and have suggested certain solutions including collaborative approaches and alternative study designs to mitigate these challenges.http://link.springer.com/article/10.1186/s13014-020-01538-y |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Srinivas Chilukuri Pankaj Kumar Panda Rakesh Jalali |
spellingShingle |
Srinivas Chilukuri Pankaj Kumar Panda Rakesh Jalali PITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy Radiation Oncology |
author_facet |
Srinivas Chilukuri Pankaj Kumar Panda Rakesh Jalali |
author_sort |
Srinivas Chilukuri |
title |
PITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy |
title_short |
PITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy |
title_full |
PITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy |
title_fullStr |
PITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy |
title_full_unstemmed |
PITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy |
title_sort |
pitching (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy |
publisher |
BMC |
series |
Radiation Oncology |
issn |
1748-717X |
publishDate |
2020-06-01 |
description |
Abstract Developments in the field of proton beam therapy (PBT) have recently crossed the tipping point wherein the modality is now more versatile than ever before, with possibilities and likely indications expanding rapidly. However the pace of evidence generation lags behind the developments in the field. Generating quality evidence has its own set of challenges owing to complexities of conducting randomized controlled trials, which are the hallmark of level 1 evidence generation. Here we discuss various challenges to clinical evidence generation in PBT and have suggested certain solutions including collaborative approaches and alternative study designs to mitigate these challenges. |
url |
http://link.springer.com/article/10.1186/s13014-020-01538-y |
work_keys_str_mv |
AT srinivaschilukuri pitchingprofessionalorganisationsinnovativetrialdesignsandcollaborativeapproachforevidencegenerationforprotontherapy AT pankajkumarpanda pitchingprofessionalorganisationsinnovativetrialdesignsandcollaborativeapproachforevidencegenerationforprotontherapy AT rakeshjalali pitchingprofessionalorganisationsinnovativetrialdesignsandcollaborativeapproachforevidencegenerationforprotontherapy |
_version_ |
1724577210920075264 |