The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial
Objective: The objective is to study the role of antibiotic prophylaxis, if any, in the prevention of wound infection after open mesh repair of primary inguinal hernias. Materials and Methods: Patients coming to outpatient department for open mesh repair of inguinal hernia were randomized into the p...
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Wolters Kluwer Medknow Publications
2021-01-01
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Online Access: | http://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2021;volume=27;issue=1;spage=5;epage=8;aulast=Jain |
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doaj-b8acfbc77ce3459aa27e495b8e9442882021-03-31T07:34:48ZengWolters Kluwer Medknow PublicationsNigerian Journal of Surgery1117-68062021-01-012715810.4103/njs.NJS_52_19The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trialSudhir Kumar JainTariq HameedDhruv JainMohak SinghAdiba NizamObjective: The objective is to study the role of antibiotic prophylaxis, if any, in the prevention of wound infection after open mesh repair of primary inguinal hernias. Materials and Methods: Patients coming to outpatient department for open mesh repair of inguinal hernia were randomized into the placebo group and antibiotic group, a total of 150 patients were enrolled in the study. Follow-up was done up to 1 month to look for any evidence of surgical site infection using the criteria of Centers for Disease Control on wound infection. Results: Twelve patients in the antibiotic group and nine patients in the placebo group were found to have evidence of surgical site infection. This difference was found to be insignificant with P = 0.14. Three patients in the placebo group developed deep surgical site infection but on analysis, this difference was also found to be insignificant with P = 0.122.None of these patients required mesh removal. Conclusion: The result of the present study suggests that the use of prophylactic antibiotics during mesh repair of primary inguinal hernias does not give any extra protection from infections. Multicenter meta-analysis is required to give definite guidelines regarding the use of prophylactic antibiotics.http://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2021;volume=27;issue=1;spage=5;epage=8;aulast=Jainantibioticmesh inguinal hernia repairprophylaxis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sudhir Kumar Jain Tariq Hameed Dhruv Jain Mohak Singh Adiba Nizam |
spellingShingle |
Sudhir Kumar Jain Tariq Hameed Dhruv Jain Mohak Singh Adiba Nizam The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial Nigerian Journal of Surgery antibiotic mesh inguinal hernia repair prophylaxis |
author_facet |
Sudhir Kumar Jain Tariq Hameed Dhruv Jain Mohak Singh Adiba Nizam |
author_sort |
Sudhir Kumar Jain |
title |
The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
title_short |
The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
title_full |
The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
title_fullStr |
The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
title_full_unstemmed |
The role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: A prospective double-blind randomized placebo-controlled trial |
title_sort |
role of antibiotic prophylaxis in lichtenstein repair of primary inguinal hernia: a prospective double-blind randomized placebo-controlled trial |
publisher |
Wolters Kluwer Medknow Publications |
series |
Nigerian Journal of Surgery |
issn |
1117-6806 |
publishDate |
2021-01-01 |
description |
Objective: The objective is to study the role of antibiotic prophylaxis, if any, in the prevention of wound infection after open mesh repair of primary inguinal hernias. Materials and Methods: Patients coming to outpatient department for open mesh repair of inguinal hernia were randomized into the placebo group and antibiotic group, a total of 150 patients were enrolled in the study. Follow-up was done up to 1 month to look for any evidence of surgical site infection using the criteria of Centers for Disease Control on wound infection. Results: Twelve patients in the antibiotic group and nine patients in the placebo group were found to have evidence of surgical site infection. This difference was found to be insignificant with P = 0.14. Three patients in the placebo group developed deep surgical site infection but on analysis, this difference was also found to be insignificant with P = 0.122.None of these patients required mesh removal. Conclusion: The result of the present study suggests that the use of prophylactic antibiotics during mesh repair of primary inguinal hernias does not give any extra protection from infections. Multicenter meta-analysis is required to give definite guidelines regarding the use of prophylactic antibiotics. |
topic |
antibiotic mesh inguinal hernia repair prophylaxis |
url |
http://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2021;volume=27;issue=1;spage=5;epage=8;aulast=Jain |
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