Miltefosine-Lopinavir Combination Therapy Against Leishmania infantum Infection: In vitro and in vivo Approaches

Miltefosine-Lopinavir Combination Therapy Against Leishmania infantum Infection: In vitro and in vivo Approaches

Concurrently, leishmaniasis and AIDS are global public health issues and the overlap between these diseases adds additional treats to the management of co-infected patients. Lopinavir (LPV) has a well characterized anti-HIV and leishmanicidal action, and to analyze its combined action with miltefosi...

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Bibliographic Details
Main Authors: Karina M. Rebello, Valter V. Andrade-Neto, Claudia Regina B. Gomes, Marcos Vinícius N. de Souza, Marta H. Branquinha, André L. S. Santos, Eduardo Caio Torres-Santos, Claudia M. d'Avila-Levy
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
chemotherapy
co-infection
HIV
HIV-PI
leishmaniasis
treatment
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00229/full

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