Genetic variation in the renin—angiotensin system, use of renin—angiotensin system inhibitors and the risk of myocardial infarction

Genetic variation in the renin—angiotensin system, use of renin—angiotensin system inhibitors and the risk of myocardial infarction

Introduction. This study investigated whether variation in the genes encoding for ACE, AGT and AGTR1 modifies the risk of myocardial infarction (MI) related to ACE inhibitors and AT II antagonists. Methods. A nested case-control study among users of antihypertensive drugs, in whom the polymorphisms...

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Main Authors: Anke-Hilse Maitland-van der Zee, Diane BMA van Wieren-de Wijer, Anthonius de Boer, Abraham A Kroon, Peter W de Leeuw, Paul Schiffers, Rob GJH Janssen, Bruce M Psaty, Cornelia M van Duijn, Bruno HCh Stricker, Olaf H Klungel
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2011-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320310391834

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