Two South Indian children with KCNT1-related malignant migrating focal seizures of infancy – Clinical characteristics and outcome of targeted treatment with quinidine

Two South Indian children with KCNT1-related malignant migrating focal seizures of infancy – Clinical characteristics and outcome of targeted treatment with quinidine

KCNT1 gene encodes a sodium-gated potassium channel subunit that plays an important role in regulating excitability in neurons. Quinidine is a partial antagonist of this channel. We report the clinical characteristics of two south Indian children with KCNT1-related epileptic encephalopathy. Both of...

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Bibliographic Details
Main Authors: Abhijit Anil Patil, K P Vinayan, Arun Grace Roy
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Epileptic encephalopathy
KCNT1
quinidine
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2019;volume=22;issue=3;spage=311;epage=315;aulast=Patil

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