Protective efficacy of Newcastle disease virus expressing soluble trimeric hemagglutinin against highly pathogenic H5N1 influenza in chickens and mice.

Protective efficacy of Newcastle disease virus expressing soluble trimeric hemagglutinin against highly pathogenic H5N1 influenza in chickens and mice.

BACKGROUND: Highly pathogenic avian influenza virus (HPAIV) causes a highly contagious often fatal disease in poultry, resulting in significant economic losses in the poultry industry. HPAIV H5N1 also poses a major public health threat as it can be transmitted directly from infected poultry to human...

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Bibliographic Details
Main Authors: Lisette A H M Cornelissen, Olav S de Leeuw, Mirriam G Tacken, Heleen C Klos, Robert P de Vries, Els A de Boer-Luijtze, Diana J van Zoelen-Bos, Alan Rigter, Peter J M Rottier, Rob J M Moormann, Cornelis A M de Haan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3429475?pdf=render

Internet

http://europepmc.org/articles/PMC3429475?pdf=render

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