Lack of association between serum syndecan-4, myocardial fibrosis and ventricular dysfunction in subjects with chronic Chagas disease.

Lack of association between serum syndecan-4, myocardial fibrosis and ventricular dysfunction in subjects with chronic Chagas disease.

Syndecan-4 is a transmembrane glycoprotein associated with inflammation and fibrosis. Increased syndecan-4 levels were previously detected after acute myocardial infarction and in subjects with heart failure. However, the levels of syndecan-4 in subjects with Chagas disease have not so far been inve...

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Main Authors: Ticiana Ferreira Larocca, Carolina Thé Macêdo, Márcia Noya-Rabelo, Luís Cláudio Lemos Correia, Moisés Imbassahy Moreira, Alessandra Carvalho Caldas, Jorge Andion Torreão, Bruno Solano de Freitas Souza, Juliana Fraga Vasconcelos, Alexandre Schaer Carvalho da Silva, Ricardo Ribeiro Dos Santos, Milena Botelho Pereira Soares
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5726626?pdf=render

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