N-Acetyltransferase 10 Promotes Micronuclei Formation to Activate the Senescence-Associated Secretory Phenotype Machinery in Colorectal Cancer Cells
The formation of micronuclei (MN) is prevalent in human cancer cells and its role in activating the senescence-associated secretory phenotype (SASP) machinery has been identified recently. However, the role of MN in regulation of SASP signaling still needs to define in practical cancers. Here, we re...
Main Authors: | Yanan Cao, Mengfei Yao, Yaqian Wu, Ningning Ma, Haijing Liu, Bo Zhang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-08-01
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Series: | Translational Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S193652332030084X |
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