Grape seed extract ameliorates PhIP-induced colonic injury by modulating gut microbiota, lipid metabolism, and NF-κB signaling pathway in rats
2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) is a common carcinogen produced in thermally processed protein-rich foods. This study explored the protective effects of grape seed extract (GSE) against colonic injury induced by short-term exposure to PhIP and the underlying mechanisms involv...
Main Authors: | Xiuli Zhao, Yuekun Wu, Hengchao Liu, Nan Hu, Yan Zhang, Shuo Wang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
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Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464621000116 |
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