Molecular subtypes and clinicopathological features of breastcancer
Breast cancer is a heterogeneous disease with regard to morphological spectrum, clinical presentation and response to therapy. Based on immunohistochemistry detection of estrogen receptor, progesterone receptor, Her-2 status, proliferation rate and clusters of basal gene expression, breast cancers c...
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Universitas Gadjah Mada
2013-04-01
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| Series: | Journal of the Medical Sciences |
| Online Access: | https://jurnal.ugm.ac.id/bik/article/view/3376 |
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doaj-b8637e5e695243c8a01796557874d3c82020-11-24T22:42:41ZengUniversitas Gadjah MadaJournal of the Medical Sciences0126-13122356-39312013-04-01450110.19106/JMedScie0045012013063014Molecular subtypes and clinicopathological features of breastcancer. IrianiwatiBreast cancer is a heterogeneous disease with regard to morphological spectrum, clinical presentation and response to therapy. Based on immunohistochemistry detection of estrogen receptor, progesterone receptor, Her-2 status, proliferation rate and clusters of basal gene expression, breast cancers can be classified into luminal A, luminal B, basal-like/triple negative, and Her-2 positive. It was suggested that there was a close relationship between molecular subtypes and clinicopathological features of breast cancer, as they are very important to predict prognosis and therapeutic implications. Keywords: molecular subtypes - breast cancer- clinicopathological features -heterogeneity –theraputicimplicationshttps://jurnal.ugm.ac.id/bik/article/view/3376 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
. Irianiwati |
| spellingShingle |
. Irianiwati Molecular subtypes and clinicopathological features of breastcancer Journal of the Medical Sciences |
| author_facet |
. Irianiwati |
| author_sort |
. Irianiwati |
| title |
Molecular subtypes and clinicopathological features of breastcancer |
| title_short |
Molecular subtypes and clinicopathological features of breastcancer |
| title_full |
Molecular subtypes and clinicopathological features of breastcancer |
| title_fullStr |
Molecular subtypes and clinicopathological features of breastcancer |
| title_full_unstemmed |
Molecular subtypes and clinicopathological features of breastcancer |
| title_sort |
molecular subtypes and clinicopathological features of breastcancer |
| publisher |
Universitas Gadjah Mada |
| series |
Journal of the Medical Sciences |
| issn |
0126-1312 2356-3931 |
| publishDate |
2013-04-01 |
| description |
Breast cancer is a heterogeneous disease with regard to morphological spectrum, clinical presentation and response to therapy. Based on immunohistochemistry detection of estrogen receptor, progesterone receptor, Her-2 status, proliferation rate and clusters of basal gene expression, breast cancers can be classified into luminal A, luminal B, basal-like/triple negative, and Her-2 positive. It was suggested that there was a close relationship between molecular subtypes and clinicopathological features of breast cancer, as they are very important to predict prognosis and therapeutic implications.
Keywords: molecular subtypes - breast cancer- clinicopathological features -heterogeneity –theraputicimplications |
| url |
https://jurnal.ugm.ac.id/bik/article/view/3376 |
| work_keys_str_mv |
AT irianiwati molecularsubtypesandclinicopathologicalfeaturesofbreastcancer |
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