High levels of interleukin-6 in patients with rheumatoid arthritis are associated with greater improvements in health-related quality of life for sarilumab compared with adalimumab

High levels of interleukin-6 in patients with rheumatoid arthritis are associated with greater improvements in health-related quality of life for sarilumab compared with adalimumab

Abstract Background Increased levels of cytokines, including interleukin-6 (IL-6), reflect inflammation and have been shown to be predictive of therapeutic responses, fatigue, pain, and depression in patients with rheumatoid arthritis (RA), but limited data exist on associations between IL-6 levels...

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Bibliographic Details
Main Authors: Vibeke Strand, Susan H. Boklage, Toshio Kimura, Florence Joly, Anita Boyapati, Jérôme Msihid
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Interleukin-6
Sarilumab
Morning stiffness
Fatigue
Physical function
Online Access:http://link.springer.com/article/10.1186/s13075-020-02344-3

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