IL-4 attenuates pulmonary epithelial cell-mediated suppression of T cell priming.

IL-4 attenuates pulmonary epithelial cell-mediated suppression of T cell priming.

We have previously shown that Th2-polarized airway inflammation facilitates sensitization towards new, protein antigens. In this context, we could demonstrate that IL-4 needs to act on cells of the hematopoetic and the structural compartment in order to facilitate sensitization towards new antigens....

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Bibliographic Details
Main Authors: Melanie Albrecht, Markus Arnhold, Sandra Lingner, Subhashree Mahapatra, Dunja Bruder, Gesine Hansen, Anna-Maria Dittrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3447776?pdf=render

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