Image-Derived Input Functions for Quantification of A1 Adenosine Receptors Availability in Mice Brains Using PET and [18F]CPFPX

Image-Derived Input Functions for Quantification of A1 Adenosine Receptors Availability in Mice Brains Using PET and [18F]CPFPX

PurposeIn vivo imaging for the A1 adenosine receptors (A1ARs) with positron emission tomography (PET) using 8-cyclopentyl-3-(3-[18F]fluoropropyl)-1-propylxan- thine ([18F]CPFPX) has become an important tool for studying physiological processes quantitatively in mice. However, the measurement of arte...

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Bibliographic Details
Main Authors: Xuan He, Franziska Wedekind, Tina Kroll, Angela Oskamp, Simone Beer, Alexander Drzezga, Johannes Ermert, Bernd Neumaier, Andreas Bauer, David Elmenhorst
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Physiology
Subjects:
image-derived input function
positron emission tomography
A1 adenosine receptors
[18F]CPFPX
mice brains
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01617/full

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