What Is Inflammatory Breast Cancer? Revisiting the Case Definition

What Is Inflammatory Breast Cancer? Revisiting the Case Definition

The case definition for inflammatory breast cancer (IBC) is controversial. The American Joint Committee on Cancer defines IBC as redness, warmth and edema involving at least half the breast. The SEER program relies on a pathologic finding of dermal lymphatic invasion and recently added those with cl...

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Bibliographic Details
Main Authors: Paul H. Levine, Ladan Zolfaghari, Heather Young, Muhannad Hafi, Timothy Cannon, Chitra Ganesan, Carmela Veneroso, Rachel Brem, Mark Sherman
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Cancers
Subjects:
inflammatory breast cancer
AJCC
SEER
diagnosis
biology
clinical presentation
Online Access:http://www.mdpi.com/2072-6694/2/1/143/
Description
Summary:The case definition for inflammatory breast cancer (IBC) is controversial. The American Joint Committee on Cancer defines IBC as redness, warmth and edema involving at least half the breast. The SEER program relies on a pathologic finding of dermal lymphatic invasion and recently added those with clinical involvement of more than 3/4 of the breast. We established a registry to collect information and specimens from IBC patients to clarify the epidemiology and biology of these tumors. The goals of this report are to suggest improvements regarding case definitions and provide data on the variety of presentations relevant to early diagnosis.
ISSN:2072-6694

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