Evaluation of a Mathematical Model of Rat Body Weight Regulation in Application to Caloric Restriction and Drug Treatment Studies.

The purpose of this work is to develop a mathematical model of energy balance and body weight regulation that can predict species-specific response to common pre-clinical interventions. To this end, we evaluate the ability of a previously published mathematical model of mouse metabolism to describe...

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Bibliographic Details
Main Authors: Jangir Selimkhanov, W Clayton Thompson, Terrell A Patterson, John R Hadcock, Dennis O Scott, Tristan S Maurer, Cynthia J Musante
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4882007?pdf=render