Novel Compound Heterozygous PRKN Variants in a Han-Chinese Family with Early-Onset Parkinson’s Disease

Genetic factors are thought to play an important role in the pathogenesis of Parkinson’s disease (PD), particularly early-onset PD. The PRKN gene is the primary disease-causing gene for early-onset PD. The details of its functions remain unclear. This study identified novel compound heterozygous var...

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Bibliographic Details
Main Authors: Kuan Fan, Pengzhi Hu, Chengyuan Song, Xiong Deng, Jie Wen, Yiming Liu, Hao Deng
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2019/9024894