Metformin and Pioglitazone Reduce Gene Expression of Inflammatory Factors in Insulin Resistant and Hypertrophied Adipocytes

Metformin and Pioglitazone Reduce Gene Expression of Inflammatory Factors in Insulin Resistant and Hypertrophied Adipocytes

Objective: In obesity, chronic low grade inflammation, created by induction of pro-inflammatory markers, causes adipocyte dysfunction in adipose tissue. Adipocytes dysfunction is associated with various diseases including insulin resistance and obesity. In obesity, inflammatory factors such as osteo...

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Bibliographic Details
Main Authors: Zahra Malekpour-Dehkordi, Javad Mohiti-Ardekani, Yousof Naghiaee, Shahram Teimourian, Mahdie Hemati, Mitra Nourbakhsh
Format: Article
Language:English
Published: Shahid Sadoughi University of Medical Sciences 2020-12-01
Series:Iranian Journal of Diabetes and Obesity
Subjects:
angptl2
metformin
osteopontin
pioglitazone
tgf-β
Online Access:http://ijdo.ssu.ac.ir/article-1-595-en.html

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