The Cadin-2-en-1β-ol-1β-d-glucuronopyranoside Suppresses TPA-Mediated Matrix Metalloproteinase-9 Expression Through the ERK Signaling Pathway in MCF-7 Human Breast Adenocarcinoma Cells

A sesquiterpene glycoside, cadin-2-en-1β-ol-1β-D-glucuronopyranoside (known as CR4-1), was isolated from Catharanthus roseus (Apocynaceae) hairy root cultures. C. roseus is widely used as an ornamental and medicinal plant and is cultivated mainly for its alkaloids. C. roseus has been reported to hav...

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Bibliographic Details
Main Authors: Jung-Hee Kim, Man Sub Kim, Yesol Bak, Ill-Min Chung, Do-Young Yoon
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319305791