Estimating statistical significance of local protein profile-profile alignments

Estimating statistical significance of local protein profile-profile alignments

Abstract Background Alignment of sequence families described by profiles provides a sensitive means for establishing homology between proteins and is important in protein evolutionary, structural, and functional studies. In the context of a steadily growing amount of sequence data, estimating the st...

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Bibliographic Details
Main Author: Mindaugas Margelevičius
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Bioinformatics
Subjects:
Homology search
Profile-profile alignment
Random profile model
Statistical significance
Protein structure prediction
Online Access:http://link.springer.com/article/10.1186/s12859-019-2913-3

Internet

http://link.springer.com/article/10.1186/s12859-019-2913-3

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