TLR4 modulates inflammatory gene targets in the retina during Bacillus cereus endophthalmitis

TLR4 modulates inflammatory gene targets in the retina during Bacillus cereus endophthalmitis

Abstract Background Endophthalmitis is a serious intraocular infection that frequently results in significant inflammation and vision loss. Because current therapeutics are often unsuccessful in mitigating damaging inflammation during endophthalmitis, more rational targets are needed. Toll-like rece...

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Bibliographic Details
Main Authors: Phillip S. Coburn, Frederick C. Miller, Austin L. LaGrow, Salai Madhumathi Parkunan, C. Blake Randall, Rachel L. Staats, Michelle C. Callegan
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Ophthalmology
Subjects:
Bacterial endophthalmitis
Retinal gene expression
Toll-like receptor 4
Gram-positive intraocular infections
Online Access:http://link.springer.com/article/10.1186/s12886-018-0764-8

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