Two new rapid SNP-typing methods for classifying Mycobacterium tuberculosis complex into the main phylogenetic lineages.

Two new rapid SNP-typing methods for classifying Mycobacterium tuberculosis complex into the main phylogenetic lineages.

There is increasing evidence that strain variation in Mycobacterium tuberculosis complex (MTBC) might influence the outcome of tuberculosis infection and disease. To assess genotype-phenotype associations, phylogenetically robust molecular markers and appropriate genotyping tools are required. Most...

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Main Authors: David Stucki, Bijaya Malla, Simon Hostettler, Thembela Huna, Julia Feldmann, Dorothy Yeboah-Manu, Sonia Borrell, Lukas Fenner, Iñaki Comas, Mireia Coscollà, Sebastien Gagneux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3401130?pdf=render

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