Phenotypic diversity and temporal variability in a bacterial signaling network revealed by single-cell FRET
We present in vivo single-cell FRET measurements in the Escherichia coli chemotaxis system that reveal pervasive signaling variability, both across cells in isogenic populations and within individual cells over time. We quantify cell-to-cell variability of adaptation, ligand response, as well as ste...
Main Authors: | Johannes M Keegstra, Keita Kamino, François Anquez, Milena D Lazova, Thierry Emonet, Thomas S Shimizu |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/27455 |
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