A simple and effective preparation of quercetin pentamethyl ether from quercetin

A simple and effective preparation of quercetin pentamethyl ether from quercetin

Among the five hydroxy (OH) groups of quercetin (3,5,7,3',4'-pentahydroxyflavone), the OH group at 5 position is the most resistant to methylation due to its strong intramolecular hydrogen bonding with the carbonyl group at 4 position. Thus, it is generally difficult to synthesize the pent...

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Bibliographic Details
Main Authors: Jin Tatsuzaki, Tomohiko Ohwada, Yuko Otani, Reiko Inagi, Tsutomu Ishikawa
Format: Article
Language:English
Published: Beilstein-Institut 2018-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
computational calculation
per-O-methylation
quercetin
quercetin pentamethyl ether
reactivity
Online Access:https://doi.org/10.3762/bjoc.14.291

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