Multiple advantageous amino acid variants in the NAT2 gene in human populations.
BACKGROUND: Genetic variation at NAT2 has been long recognized as the cause of differential ability to metabolize a wide variety of drugs of therapeutic use. Here, we explore the pattern of genetic variation in 12 human populations that significantly extend the geographic range and resolution of pre...
Main Authors: | Francesca Luca, Giuseppina Bubba, Massimo Basile, Radim Brdicka, Emmanuel Michalodimitrakis, Olga Rickards, Galina Vershubsky, Lluis Quintana-Murci, Andrey I Kozlov, Andrea Novelletto |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2527519?pdf=render |
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