Development of paclitaxel-loaded poly(lactic acid)/hydroxyapatite core–shell nanoparticles as a stimuli-responsive drug delivery system

Development of paclitaxel-loaded poly(lactic acid)/hydroxyapatite core–shell nanoparticles as a stimuli-responsive drug delivery system

Biodegradable nanoparticles have been well studied as biocompatible delivery systems. Nanoparticles of less than 200 nm in size can facilitate the passive targeting of drugs to tumour tissues and their accumulation therein via the enhanced permeability and retention (EPR) effect. Recent studies have...

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Bibliographic Details
Main Authors: Sungho Lee, Tatsuya Miyajima, Ayae Sugawara-Narutaki, Katsuya Kato, Fukue Nagata
Format: Article
Language:English
Published: The Royal Society 2021-03-01
Series:Royal Society Open Science
Subjects:
biomaterials
hydroxyapatite
poly(lactic acid)
anti-cancer
drug delivery system
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.202030

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