Activation of Transient Receptor Potential Vanilloid-3 Channels in Keratinocytes Induces Pruritus in Humans

Carvacrol, a natural transient receptor potential vanilloid-3 activator, has been reported to cause pruritus in mice. This study aimed to evaluate the effects of carvacrol and various antipruritic agents in humans. A stimulation test with carvacrol, β-alanine, and histamine was performed. After appl...

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Bibliographic Details
Main Authors: Jin Cheol Kim, Han Bi Kim, Won-Sik Shim, In Suk Kwak, Bo Young Chung, Seok Young Kang, Chun Wook Park, Hye One Kim
Format: Article
Language:English
Published: Society for Publication of Acta Dermato-Venereologica 2021-08-01
Series:Acta Dermato-Venereologica
Subjects:
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3855