Split End Family RNA Binding Proteins: Novel Tumor Suppressors Coupling Transcriptional Regulation with RNA Processing

Split End Family RNA Binding Proteins: Novel Tumor Suppressors Coupling Transcriptional Regulation with RNA Processing

Split End (SPEN) family proteins have three members: SPEN, RBM15, and RBM15B. SPEN family proteins contain three conserved RNA recognition motifs on the N-terminal region and an SPOC domain on the C-terminal region. RBM15 is fused to MKL1 in chromosome translocation t (1;22), which causes childhood...

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Bibliographic Details
Main Authors: Hairui Su, Yanyan Liu, Xinyang Zhao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Cancer Translational Medicine
Subjects:
RNA processing
Split End
tumor suppressors
Online Access:http://www.cancertm.com/article.asp?issn=2395-3977;year=2015;volume=1;issue=1;spage=21;epage=25;aulast=Su

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