The Enigma of Tripeptidyl-Peptidase II: Dual Roles in Housekeeping and Stress

The tripeptidyl-peptidase II complex consists of repeated 138 kDa subunits, assembled into two twisted strands that form a high molecular weight complex (>5 MDa). TPPII, like many other cytosolic peptidases, plays a role in the ubiquitin-proteasome pathway downstream of the proteasome as well as...

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Bibliographic Details
Main Authors: Giulio Preta, Rainier de Klark, Riccardo Gavioli, Rickard Glas
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2010/128478