Fractional anisotropy shows differential reduction in frontal-subcortical fiber bundles - A longitudinal MRI study of 76 middle-aged and older adults

Fractional anisotropy shows differential reduction in frontal-subcortical fiber bundles - A longitudinal MRI study of 76 middle-aged and older adults

Motivated by the frontal- and white matter (WM) retrogenesis hypotheses and the as- sumptions that fronto-striatal circuits are especially vulnerable in normal aging, the goal of the present study was to identify fiber bundles connecting subcortical nuclei and frontal ar- eas and obtain site-specifi...

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Bibliographic Details
Main Authors:	Alexandra eVik, Erlend eHodneland, Judit eHaász, Martin eYstad, Astri Johansen Lundervold, Arvid eLundervold
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-05-01
Series:	Frontiers in Aging Neuroscience
Subjects:	tractography Diffusion Weighted Imaging fractional anisotropy healthy aging longitudinal study 3D MRI
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00081/full

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