Short telomeres correlate with a strong induction of cellular senescence in human dental follicle cells

Short telomeres correlate with a strong induction of cellular senescence in human dental follicle cells

Abstract Background Dental follicle cells (DFCs) are dental stem cells and interesting options for regenerative therapies in dentistry. However, DFCs acquire replicative senescence in long-term cultures, but little is known about molecular processes. In previous studies, we observed that DFC cell li...

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Bibliographic Details
Main Authors: Christian Morsczeck, Anja Reck, Torsten E. Reichert
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Molecular and Cell Biology
Subjects:
Dental follicle cells
Cellular senescence
DNA damage
Telomere length
Online Access:http://link.springer.com/article/10.1186/s12860-019-0185-4

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http://link.springer.com/article/10.1186/s12860-019-0185-4

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