Synchronous double primary malignant tumours of the tongue and lung: a case report and literature review

• Main Authors: ZHANG Qianyu, YANG Peixin, CHEN Boshen, WANG lin, HUANG Zhiquan
• Format: Article
• Language: zho
• Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2020-09-01
• Series: 口腔疾病防治
• Subjects: tongue，; tumor，; adenoid cystic carcinoma，; lung adenocarcinoma ，; double primary malignant tumor，; simultaneous surgical resection，; prognosis，
• Online Access: http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2020.09.007

Objective To investigate the diagnosis and treatment of synchronous double primary malignant tumours of the tongue and lung.Methods A case of adenoid cystic carcinoma（ACC） and lung adenocarcinoma with double primary malignancy was retrospectively analyzed.Results The tumor of patient′s tongue base gradually grew. MRI showed multiple enlarged lymph nodes on both sides of neck. CT of the chest showed obvious lesions in the anterior basal segment of the right lower lobe. The pathological biopsy of the tongue mass identified ACC, and pathological biopsy of the lung mass identified lung adenocarcinoma. The tongue and lung tumors were both surgically resected, and the tongue defect was repaired at the same time. No residue was found after surgery, and no recurrence was found during the follow-up period. The aesthetic and functional restoration of the lingual region was good.Conclusion There are few cases of adenoid cystic carcinoma and lung adenocarcinoma with double primary malignancies, and the related diagnosis and treatment are very difficult; the simultaneous removal of double primary malignant tumors may achieve good prognosis.