Poly(ethylene glycol)-modified silk fibroin membrane as a carrier for limbal epithelial stem cell transplantation in a rabbit LSCD model

Poly(ethylene glycol)-modified silk fibroin membrane as a carrier for limbal epithelial stem cell transplantation in a rabbit LSCD model

Abstract Background Limbal epithelial stem cells (LESCs) play important roles in corneal epithelial homeostasis and regeneration, and damage to the limbus will lead to limbal stem cell deficiency (LSCD), with conjunctivalization and even visual impairment. Cultured LESCs have been used for ocular su...

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Bibliographic Details
Main Authors: Yijian Li, Yuli Yang, Lei Yang, Yuxiao Zeng, Xiaowei Gao, Haiwei Xu
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Stem Cell Research & Therapy
Subjects:
Silk fibroin membrane
Poly(ethylene glycol)
Limbal epithelial stem cells
Culture methods
Limbal stem cell deficiency
Transplantation
Online Access:http://link.springer.com/article/10.1186/s13287-017-0707-y

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