A New Configurable Wireless Sensor System for Biomedical Applications with ISO 18000-3 Interface in 0.35 µm CMOS

• Main Authors: Tatjana Fedtschenko, Alexander Utz, Alexander Stanitzki, Andreas Hennig, Andre Lüdecke, Norbert Haas, Rainer Kokozinski
• Format: Article
• Language: English
• Published: MDPI AG 2019-09-01
• Series: Sensors
• Subjects: biosensor; potentiostat; amperometry; wireless; RFID; NFC; 13.56 MHz; ISO 18000-3
• Online Access: https://www.mdpi.com/1424-8220/19/19/4110
• ISSN: 1424-8220

This article presents a new configurable wireless sensor system. The system is used to perform amperometric measurements and send the measurement data to a handheld reader using a wireless transponder interface. The two-chip sensor system was implemented in a 0.35 μm CMOS technology. The system consists of an integrated nano-potentiostat that performs the actual measurements and an ISO 18000-3 compliant frontend that enables wireless telemetric data transmission and powering of the entire sensor system. The system was manufactured in combination with a chronoamperometric glucose sensor which allows the measurement of the glucose content in tear fluid and thus a non-invasive determination of the blood sugar level. For a range of sensor currents from 0.1 μA to 10 μA, the potentiostat achieved an accuracy of better than 5 % with a total power dissipation of less than 600 μW. With the realized antenna geometry a wireless communication distance of more than 7 cm has been achieved.