The APOE Genotype in Idiopathic Normal Pressure Hydrocephalus.

Amyloid plaque has been reported in brain biopsies from patients with idiopathic normal-pressure hydrocephalus (iNPH) and proposed as a significant feature of the pathophysiology. Presence of the apolipoprotein E ε4 (APOE ε4) allele is associated with increased risk of Alzheimer's disease (AD)....

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Bibliographic Details
Main Authors: Yi Yang, Mats Tullberg, Kirsten Mehlig, Annika Rosengren, Kjell Torén, Henrik Zetterberg, Carsten Wikkelsö
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4956274?pdf=render