Polymorphisms C677T and A1298C of Gene: Homocysteine Levels and Prothrombotic Biomarkers in Coronary and Pulmonary Thromboembolic Disease

Polymorphisms C677T and A1298C of Gene: Homocysteine Levels and Prothrombotic Biomarkers in Coronary and Pulmonary Thromboembolic Disease

The activity of the enzyme methylenetetrahydrofolate reductase (MTHFR) determines homocysteine (Hcy) levels, and polymorphisms in its gene affect the activity of the enzyme. Changes in the enzyme’s activity may lead to a higher susceptibility to develop arterial and venous thromboembolic disease. Th...

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Bibliographic Details
Main Authors: Eulo Lupi-Herrera MD, María Elena Soto-López MD, Msc, PhD, Antonio de Jesús Lugo-Dimas MD, Marcela Elizabeth Núñez-Martínez MD, Ricardo Gamboa PhD, Claudia Huesca-Gómez PhD, Lilia Mercedes Sierra-Galán MD, Verónica Guarner-Lans PhD
Format: Article
Language:English
Published: SAGE Publishing 2019-03-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/1076029618780344

Internet

https://doi.org/10.1177/1076029618780344

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