Suppression of Rap1 impairs cardiac myofibrils and conduction system in zebrafish.

Suppression of Rap1 impairs cardiac myofibrils and conduction system in zebrafish.

Numerous studies have revealed that Rap1 (Ras-proximate-1 or Ras-related protein 1), a small GTPase protein, plays a crucial role in mediating cAMP signaling in isolated cardiac tissues and cell lines. However, the involvement of Rap1 in the cardiac development in vivo is largely unknown. By injecti...

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Bibliographic Details
Main Authors: Wei Dong, Zhenglin Yang, Fan Yang, Jialiang Wang, Yan Zhuang, Chongren Xu, Bo Zhang, Xiao-Li Tian, Dong Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511394?pdf=render

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